Professor, Division of Neonatology, Department of Pediatrics, and Associate Member, Department of Psychology, University of British Columbia
Brain, Behaviour and Development
BC Children’s Hospital Research Institute
4480 Oak Street
Vancouver, BC V6H 3V4
Early stress in immature infants, both animal and human, has the potential for long-term effects. Medical care of infants born very prematurely (< 33 weeks gestation) involves systematic repeated exposure to noxious procedures that frequently induce stress and pain. Pain in biologically immature neonates induces numerous physiologic, endocrine and behavioral changes that may contribute to changes in neurodevelopment - affecting the developing brain, self-regulation, cognition and behavior. These difficulties impact on the infant's adjustment to the environment, parent-infant interaction and long-term outcomes, however the etiology is largely unknown. Using a biobehavioural multidisciplinary approach we have gained new knowledge about relationships between neonatal pain, clinical factors and outcomes in children born very preterm.
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